Studies on table grape germplasm grown in Northern Greece. 2. Seedlessness, berry and must characteristics

From 1991 to 1993 nine quantitative and qualitative characteristics of the grape berry and its must were evaluated using local and introduced table grape cultivars of the grapevine collection of the Greek Gene Bank. The data indicate a distinct variation in the grape germplasm in all characters and demonstrate the usefulness of the genetic material as a donor of important genes for grapevine improvement. Principal Component Analysis (PCA) produced 2 factors representing 68.1% of the total variation. PC1, explaining 43.6% of the total variance, is highly correlated with berry size parameters and characteristics of the berry structure. By Cluster Analysis the assessed cultivars were separated into distinct groups; while seedlessness, was associated with small berry detachment force from the pedicel, late maturity was combined with high acid and low sugar content and a large number of seeds per berry was accompanied by low sugar content

Studies on table grape germplasm grown in Northern Greece. I. Maturity time, bunch characteristics and yield

41 local and introduced table grape cultivars of the Greek Gene Bank in Thessaloniki were evaluated and documented with regard to 10 important morphological and viticultural characteristics, e.g. maturity time, bunch form and crop yield from 1991 tb 1993. The data indicate great variation within the grape germplasm in all characters and stress the importance of the genetic material as a donor of valuable genes for further grapevine improvement. Among the earliest cultivars is the Greek newbred Attiki (harvest time: end of July), while the local traditional Sideritis was shown to be the latest maturing cultivar (end of October). Principal Component Analysis (PCA) showed 3 factors representing 69.6% of the total variation. PC1, explaining 40.6% of the total variance, is highly correlated with time of maturity and crop yield. PC2, may be considered as the bunch size factor. The assessed cultivars were classified by cluster analysis into distinct groups, 2 of which contained all early and most of the late season cultivars

Insights into the multitrophic interactions between the biocontrol agent Bacillus subtilis MBI 600, the pathogen Botrytis cinerea and their plant host

Botrytis cinerea is a plant pathogen causing the gray mold disease in a plethora of host plants. The control of the disease is based mostly on chemical pesticides, which are responsible for environmental pollution, while they also pose risks for human health. Furthermore, B. cinerea resistant isolates have been identified against many fungicide groups, making the control of this disease challenging. The application of biocontrol agents can be a possible solution, but requires deep understanding of the molecular mechanisms in order to be effective. In this study, we investigated the multitrophic interactions between the biocontrol agent Bacillus subtilis MBI 600, a new commercialized biopesticide, the pathogen B. cinerea and their plant host. Our analysis showed that this biocontrol agent reduced B. cinerea mycelial growth in vitro, and was able to suppress the disease incidence on cucumber plants. Moreover, treatment with B. subtilis led to induction of genes involved in plant immunity. RNAseq analysis of B. cinerea transcriptome upon exposure to bacterial secretome, showed that genes coding for MFS and ABC transporters were highly induced. Deletion of the Bcmfs1 MFS transporter gene, using a CRISP/Cas9 editing method, affected its virulence and the tolerance of B. cinerea to bacterial secondary metabolites. These findings suggest that specific detoxification transporters are involved in these interactions, with crucial role in different aspects of B. cinerea physiology

Coupled wave-2D hydrodynamics modeling at the Reno River mouth (Italy) under climate change scenarios

This work presents the results of the numerical study implemented for the natural area of Lido di Spina, a touristic site along the Italian coast of the North Adriatic Sea, close to the mouth of River Reno. High-resolution simulations of nearshore dynamics are carried out under climate change conditions estimated for the site. The adopted modeling chain is based on the implementation of multiple-nested, open-source numerical models. More specifically, the coupled wave-2D hydrodynamics runs, using the open-source TELEMAC suite, are forced at the offshore boundary by waves resulting from the wave model (SWAN) simulations for the Adriatic Sea, and sea levels computed following a joint probability analysis approach. The system simulates presentday scenarios, as well as conditions reflecting the high IPCC greenhouse concentration trajectory named RCP8.5 under predicted climate changes. Selection of sea storms directed from SE (Sirocco events) and E-NE (Bora events) is performed together with Gumbel analysis, in order to define ordinary and extreme sea conditions. The numerical results are here presented in terms of local parameters such as wave breaking position, alongshore currents intensity and direction and flooded area, aiming to provide insights on how climate changes may impact hydrodynamics at a site scale. Although the wave energy intensity predicted for Sirocco events is expected to increase only slightly, modifications of the wave dynamics, current patterns, and inland flooding induced by climate changes are expected to be significant for extreme conditions, especially during Sirocco winds, with an increase in the maximum alongshore currents and in the inundated area compared to past conditions. \ua9 2018 by the authors

A network-aware framework for energy-efficient data acquisition in wireless sensor networks

Wireless sensor networks enable users to monitor the physical world at an extremely high fidelity. In order to collect the data generated by these tiny-scale devices, the data management community has proposed the utilization of declarative data-acquisition frameworks. While these frameworks have facilitated the energy-efficient retrieval of data from the physical environment, they were agnostic of the underlying network topology and also did not support advanced query processing semantics. In this paper we present KSpot+, a distributed network-aware framework that optimizes network efficiency by combining three components: (i) the tree balancing module, which balances the workload of each sensor node by constructing efficient network topologies; (ii) the workload balancing module, which minimizes data reception inefficiencies by synchronizing the sensor network activity intervals; and (iii) the query processing module, which supports advanced query processing semantics. In order to validate the efficiency of our approach, we have developed a prototype implementation of KSpot+ in nesC and JAVA. In our experimental evaluation, we thoroughly assess the performance of KSpot+ using real datasets and show that KSpot+ provides significant energy reductions under a variety of conditions, thus significantly prolonging the longevity of a WSN

Fuel consumption and CO2 emissions of passenger cars over the New Worldwide Harmonized Test Protocol

AbstractIn 2014 the United Nations Economic Commission for Europe (UNECE) adopted the global technical regulation No. 15 concerning the Worldwide harmonized Light duty Test Procedure (WLTP). Having significantly contributed to its development, the European Commission is now aiming at introducing the new test procedure in the European type-approval legislation for light duty vehicles in order to replace the New European Driving Cycle (NEDC) as the certification test.The current paper aims to assess the effect of WLTP introduction on the reported CO2 emissions from passenger cars presently measured under the New European Driving Cycle and the corresponding test protocol. The most important differences between the two testing procedures, apart from the kinematic characteristics of the respective driving cycles, is the determination of the vehicle inertia and driving resistance, the gear shifting sequence, the soak and test temperature and the post-test charge balance correction applied to WLTP. In order to quantify and analyze the effect of these differences in the end value of CO2 emissions, WLTP and NEDC CO2 emission measurements were performed on 20 vehicles, covering almost the whole European market. WLTP CO2 values range from 125.5 to 217.9g/km, NEDC values range from 105.4 to 213.2g/km and the ΔCO2 between WLTP and NEDC ranges from 4.7 to 29.2g/km for the given vehicle sample. The average cold start effect over WLTP was found 6.1g/km, while for NEDC it was found 12.3g/km. For a small gasoline and a medium sized diesel passenger car, the different inertia mass and driving resistance is responsible 63% and 81% of the observed ΔCO2 between these two driving cycles respectively, whereas the other parameters (driving profile, gear shifting, test temperature) account for the remaining 37% and 19%

A nutrition intervention is effective in improving dietary components linked to cardiometabolic risk in youth with first-episode psychosis

© The Authors 2016. Severe mental illness is characterised by a 20-year mortality gap due to cardiometabolic disease. Poor diet in those with severe mental illness is an important and modifiable risk factor. The present study aimed to (i) examine baseline nutritional intake in youth with first-episode psychosis (FEP), (ii) evaluate the feasibility and acceptability of nutritional intervention early in FEP and (iii) to evaluate the effectiveness of early dietary intervention on key nutritional end points. Participants were recruited over a 12-month period from a community-based programme specifically targeting young people aged 15-25 years with newly diagnosed FEP. Individual dietetic consultations and practical group sessions were offered as part of a broader lifestyle programme. Dietary assessments were conducted before and at the end of the 12-week intervention. Participants exceeded recommended energy and Na intakes at baseline. Retention within the nutrition intervention was 67 %, consistent with other interventions offered to FEP clients. There was a 47 % reduction in discretionary food intake (-94 g/d, P<0·001) and reductions in daily energy (-24 %, P<0·001) and Na (-26 %, P<0·001) intakes. Diet quality significantly improved, and the mean change was 3·6 (95 % CI 0·2, 6·9, P<0·05), although this finding was not significant after Bonferroni's correction. Increased vegetable intake was the main factor contributing to improved diet quality. Nutrition intervention delivered shortly after initiation of antipsychotic medication is feasible, acceptable and effective in youth with FEP. Strategies to prevent weight gain and metabolic decline will contribute to prevent premature cardiometabolic disease in this vulnerable population

Selective Intra-arterial Chemotherapy with Floxuridine as Second- or Third-Line Approach in Patients with Unresectable Colorectal Liver Metastases

Background: An outcome assessment was performed of patients with unresectable colorectal liver metastases (CRLM) treated in second or third line with floxuridine (FUDR)-based hepatic artery infusion (HAI). Methods: Twenty-three patients who were pretreated with systemic (immuno)chemotherapy received FUDR-HAI alone or combined with systemic chemotherapy. We reviewed patient charts and our prospective patient database for survival and associated risk factors. Results: Patients received FUDR-HAI for unresectable CRLM from January 2000 to September 2010. Twelve patients (52%) received concurrent systemic chemotherapy. Median overall survival (OS), progression-free survival (PFS), and hepatic PFS were 15.6months (range, 2.5-55.7months), 3.9months (range, 0.7-55.7months), and 5.5months (range, 1.6-55.7months), respectively. The liver resection rate after HAI was 35%. PFS was better in patients undergoing secondary resection than in patients without resection (hazard ratio [HR] 0.21; 95% confidence interval [95% CI] 0.07-0.66; P=0.0034), while OS showed a trend toward improvement (HR 0.4; 95% CI 0.13-1.2; P=0.09). No differences were observed in OS (P=0.69) or PFS (P=0.086) in patients who received FUDR-HAI alone compared with patients treated with combined regional and systemic chemotherapy. No statistically significant differences were seen in patients previously treated with one chemotherapy line compared with patients treated with two lines. Presence of extrahepatic disease was a negative risk factor for PFS (liver-only disease: HR 0.03; 95% CI 0.0032-0.28; P<0.0001). Toxicities were manageable with dose modifications and supportive measures. Conclusions: FUDR-HAI improves PFS and results in a trend toward improved OS in selected patients able to undergo liver resection after tumor is downsize

Temsirolimus Is Highly Effective as Third-Line Treatment in Chromophobe Renal Cell Cancer

We report unexpectedly high efficacy of temsirolimus as third-line treatment in a patient with metastatic chromophobe renal cell carcinoma. After failure of two sequentially administered tyrosine kinase inhibitors, treatment with temsirolimus resulted in a prolonged partial remission of 14 months, and the response is still continuing. Up to now, no data from randomized clinical studies have been published addressing the question of efficacy of temsirolimus as third-line treatment after failure of tyrosine kinase inhibitors. The case presented here implies that temsirolimus could be a viable option for patients with metastatic chromophobe renal cell carcinoma